The invention belongs to the field of insulating and fireproof material engineering, in particular to a nontoxic halogen-free low-smoke macromolecular neoprene foaming material of which the fireproof grade reaches the international UL94V-O level, and a manufacturing technique thereof. The method comprises the following steps: taking 45 percent by weight of neoprene, 5 percent by weight of flame retardant, 15 percent by weight of carbon black as a strengthening agent, 15 percent by weight of CaCo3 as a filler, 10 percent by weight of paraffin oil as a softening agent, 3 percent by weight of foaming agent, 5 percent by weight of talcum powder and 2 percent by weight of silica; mixing the raw materials, extrusion molding, vulcanization foaming and shrinkproof treating so as to obtain the macromolecular neoprene foaming material conforming to the international standard of UL94V-O. The macromolecular neoprene foaming material can be used in various kinds of insulating and fireproof material engineering after being trimmed and cut.