The invention discloses a semi-persistent scheduling method, which comprises that: when a semi-persistent scheduling periodicity is reached, an evolved node B eNB and a terminal UE select a subframe from a subframe group as the subframe for the semi-persistent scheduling, wherein the subframe group comprises a plurality of subframes, and a subframe group periodicity is equal to the semi-persistent scheduling periodicity. The semi-persistent scheduling method can prolong an interval of time conflicts between HAPQ retransmission and the semi-persistent scheduling, and also avoid other problems caused by that an upper layer needs extra cache when the semi-persistent scheduling periodicity is not matched with a data arrival interval.