This disclosure provides a differential reception system in a cellular receiver and a method for realizing signal reception thereof, including: filtering a received signal and then transforming the filtered signal into differential signals; and performing amplification and phase discrimination process of differential signals and compensating the phase of either channel differential signal, and synthesizing the processed differential signals and demodulating the synthesized signal. By means of controlling the phases of differential lines, the disclosure improves the receiving sensitivity of a differential reception system and significantly reduces the requirement for layout of the differential lines.