The invention relates to a pharmaceutical composition for treating skin (A) disease, having the strong eliminating function on bacteria, epiphyte and viruses and has the obvious effect on tinea of feet and hands, onychomycosis, tinea cruris, scald head, furuncle, mosquito bite and acrohyperhidrosis. The high-molecule material and recipe composition of the pharmaceutical composition has no poison and little stimulation on skin, has long action time and presents the actions of controlled release and stability. The quality can be kept to be stable when the composition is stored at normal temperature, and thereby, the composition is safe and effective. The composition contains the main constituents of povidone iodine, acetylsalicylic acid, polyethylene glycol, potash iodate, phenol and high-molecule material.