The invention relates to a multifunctional physical model test device of a horizontal well, comprising a main body, a real-time monitoring system, a power system, a data acquisition system and a sand production on-line monitoring system. The multifunctional physical model test device is characterized in that the main body is in a horizontal combined structure, is respectively and electrically connected with the real-time monitoring system, the data acquisition system and the and production on-line monitoring system and is controlled by the real-time monitoring system, the data acquisition system and the and production on-line monitoring system; the main body is connected with the power system through a pipeline; the power system comprises a plunger pump and a shunt tube connected with a stratum set box; the main body comprises a bracket and an outer sleeve installed on the bracket; the outer sleeve is internally provided with a sand filtering tube and a camera; and the stratum set box, a pressure sensor, a flowmeter and a sand content sensor are installed on the outer sleeve. The invention has the characteristics of more detection items, accurate data acquisition, convenient and fast operation, high automatization degree, visible operation, dynamic detection, good timeliness and the like, and is widely applied to sand prevention process of petroleum extraction.