The invention discloses a human-computer interface control panel of a hydraulic support frame controller, comprising a shell frame plate fixed on an operation platform of the controller, and an operation panel arranged at an empty frame in the middle part of the shell frame plate, wherein the operation panel is stuck with an aponeurotic film; locating isolation posts extending towards an inner cavity of the operation platform are symmetrically arranged at the connecting part between the peripheries of the shell frame plate and the operation panel, and the operation panel and a display screen locating base plate are sequentially arranged at intervals from top to bottom on the locating isolation posts; a gland bush is arranged between the combining surface of the shell frame plate and the operation panel; an observation hole is arranged on the operation panel at the position corresponding to a display screen and is provided with a transparent reinforced plate; and the transparent reinforced plate is glued with the operation panel and the aponeurotic film by seal gum. As all parts which are combined together are well sealed, the cavity of the operation platform is ensured to be in a vacuum state, and the operation panel has good functions of anti-explosion and anti-pollution.