The invention discloses a device for measuring hydrogen embritllement sensitivity of materials in a low-temperature environment, consisting of an experiment table base 2, an experiment box 8, a stress application shaft 9, a sample clamping part, a hydrogen charging interconnecting piece and a temperature measuring and adjusting device 18, wherein the sample clamping part consists of a loading clamp A5, a loading clamp B6 and a fixed clamp 4 and is arranged in the experiment box 8; the stress application shaft 9 passes through the center of the experiment box 8 from the upper part, the lower part of the stress application shaft 9 is coaxially connected with the upper part of a sample 12 through the ample clamping part, the hydrogen charging interconnecting piece passes through the center of the experiment box through the lower part, and the upper part of the hydrogen charging interconnecting piece is coaxially connected with the lower part of the sample 12 through threads; and the temperature measuring and adjusting device 18 is arranged in the experiment box 8. The device is used for measuring the change of mechanical property of the materials in a high-pressure hydrogen charging environment; no high pressure cavity is used and only a low temperature environment is provided in the cavity, so the experiment process is extremely safe and the problem of potential safe hazard caused by the high pressure cavity used in the traditional hydrogen charging experiment can be solved.