The invention discloses a realization method of a real-time memory calculation data structure of a mixed mobile power system. In the method, a real-time memory data structure conforming to a specific data format of a power system is generated in a memory of a designated system analysis server through a structural design mode and a memory mapping mode in a network environment of a local area network or a wide area network, aiming at the properties of power system elements; an HTTP protocol and an FTP protocol are utilized to transmit the data and the acquired data to calculation nodes needing to be specifically calculated in the network, wherein, the mixed transmission mode of HTTP and FTP are carried out simultaneously in the application process. In the calculation node, different process modes are adopted on the above mixed transmission mode, thus realizing efficient calculation. The realization method of the invention has low calculation cost and small maintenance work load, can well reflect the interaction of cross-domain power system data, and can be used as an important method for improving operation efficiency of power dispatching automatic systems.