The invention provides application of tetrahydrocurcumin in preparing a medicament for preventing or/and treating a set of clinical syndromes which are characterized by aggregating a variety of metabolic disturbances in an individual, such as obesity, hypertension, abnormal blood fat, abnormal saccharometabolism, has specific medicinal effect, and is a new treatment medicament which can simultaneously and effectively correct a variety of clinical disturbance factors of MS clinically.