The invention relates to a compound fluorine-containing ion exchange membrane. The exchange membrane is formed by combining a microporous membrane serving as a reinforcing material and the ion exchange resin, wherein the microporous membrane is the fluoropolymer membrane which is grafted with a material having an ion exchange function and adopts a microporous structure, and the ion exchange resin and the material which has the ion exchange function and is grafted to the microporous membrane form physical bonding and enter the micropores of the fluoropolymer membrane. The ion exchange membrane overcomes the drawbacks of low air tightness, easy separation of the ion exchange resin from the microporous membrane and the like in the conventional microporous compound membrane and has high chemical stability and excellent mechanical property and air tightness.