The invention relates to a communication system for performing peer-to-peer connection by using a home location register (HLR in short) server, and is applied in a communication management area. The system comprises a plurality of HLR servers, a visited location register (VLR in short) server and a spanned server, wherein each HLR server can be connected with the VLR server and the spanned server respectively; and the each HLR server covers different communication segments in the communication management area respectively; and a routing list is established in the each HLR server to perform the peer-to-peer connection one another. Instead of a conventional system that all slave HLR servers need a master HLR server to perform communication transfer work, two HLR servers of the communication system for performing the peer-to-peer connection by using the home location register server can directly transmit information to each other, so a crisis of failure in establishing conversation for a plurality of mobile phones due to breakdown of the master HLR server is avoided effectively.