The invention relates to a combined drug of anethole and fenofibrate drugs. A composition formed by the anethole and fenofibrate drugs or a carrier which can be accepted in pharmacy is applied to treating fatty liver diseases. When the composition is used for treating the fatty liver, not only the synergy can be achieved, but also the toxicity of the two drugs when singly used can be decreased. As proved by the pharmacodynamic experiments, the composition of the anethole and fenofibrate drugs has good therapeutic effect on fatty liver animal models, is obviously superior to the single use of the anethole and fenofibrate drugs, and is hopeful to be a novel drug for treating the fatty liver.