The invention relates to an industrial poison water detection method, belonging to the field of sewage treatment technology; the detection method comprises the following steps especially: firstly, a rule base is built according to the practical condition of a sewage plant; secondly, real-time data of field water quality is collected; finally, the measured real-time data is compared with the rule base which is built in advance, when the real-time data is matched with the data in the rule base, whether the water quality is poisonous or non-toxic is judged; in the method, according to the real-time data such as inlet pH value, COD, and aeration basin dissolved oxygen concentration, whether poison water enters can be judged by comparing the data with the rule base, and the corresponding alarming is carried out; after the poison water invasion is finished, judgment is carried out according to the rule base, the system is restored to operate normally; after practical application, the technology can solve the difficult problems what the sewage plant faces, the normal operation of the sewage treatment plant is ensued and damage of poison water to the municipal sewage treatment plant is reduced.