The invention provides a method and a device for the early warning of vehicle rear-end accidents on an expressway and relates to a GPS positioning technology, a serial communication technology, a voice multimedia technology, a picture and image processing technology and a wireless data transmission technology. The device comprises a plurality of wireless data communication stations. Each wirelessdata communication station is formed by a central processing unit, a peripheral circuit, a wireless data module 1 and a wireless data module 2. The wireless data communication stations communicate with a vehicle-mounted terminal through the wireless data module 1 and the wireless data module 2. By adopting the device of the invention, the cost is saved, the insecurity caused by the traditional used high-voltage circuit is avoided, the operation of the device is simple and practical, the extensibility is high, users are only required to operate cell phones, to push down the buttons of the wireless modules and the like, the response speed of the device is rapid and the device is suitable for handling emergency incidents on the expressway.