The invention discloses an enema liquid for treating hyperpyrexia and cough and asthma, which is prepared by using stiff silkworm, curcuma longa, cicada slough, wine-processed rhubarb, raw ephedra herb, cassia twig, gypsum, almond, earthworm, red paeony root, tangerine peel, mix-fried tatarian aster root and mix-fried liquoric root as the raw material through the following steps: firstly adding water into gypsum to decoct; after decocting, adding the decocted gypsum in other raw material medicaments which are marinate in advance to decoct; and after decocting the raw material medicaments, filtering out a medicinal liquid, i.e. the enema liquid for treating hyperpyrexia and cough and asthma. The product of the invention mainly has the effects of expelling wind and cold pathogens externally, hot and suffocating of upper, middle and lower warmer internally, clearing and descending lung qi, purging fu-organs and relieving flatulence, relieving cough and asthma and relieving dizziness and convulsion, and is suitable to treat high fever in children, cough and dyspnea and tachypnea or the diseases with symptoms of aversion to cold, lassitude, syncope with convulsion, clonic convulsion and the like. The medicament formula of the product of the invention directly guides and is applied clinically according to the principles of Chinese medicine. The clinical curative effect shows that the product of the invention has the advantages of quick response, recurrence prevention, no any toxic or side effects, obvious treating effect and valuable popularization and application.