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发明公开
CN101768131A 通过使O-硝基苯氧基羰基化合物氢化来制备苯并吗啉衍生物的方法 失效 - 放弃专利权

通过使O-硝基苯氧基羰基化合物氢化来制备苯并吗啉衍生物的方法
摘要：
本发明描述了用于制备具有通式(I)的苯并吗啉衍生物的方法，其中，R是氢、或一个C1-C10-烷基、苯基或四氢糠基的基团，Z1至Z6各自独立地是氢或一个C1-C10-烷基基团，并且X是氧或硫，该方法通过使具有通式(II)的o-硝基苯氧基羰基化合物氢化来进行，其中，R、Z1至Z6以及X如对化学式(I)所定义，其特征在于具有通式(II)的化合物用氢气在一种钼-和/或铁-和/或铝-和/或铬-掺杂的基于镍或钴的海绵金属催化剂的存在下进行氢化，？？？？？？？。
摘要（英）：

The invention discloses a method for preparing a derivative of the general formula (I)of benzo morpholines, wherein, R is hydrogen or a radical of C1-C10-alkyl, phenyl or tetrahydrofurfuryl, Each of Z1 to Z6 is independently a hydrogen or a radical of C1-C10-alkyl, and X is oxygen or sulfur, the method is performed by hydrogenating O-nitryl phenoxyl carbonyl of the general formula (II), wherein, the R, Z1 to Z6 and X are as defined in the chemical formula (I), and the present invention is characterized in that the compound of the general formula (II) is hydrogenated in existence of a sponge metal catalyst doped by molybdenum-and/or iron-and/or aluminum-and/or chromium based on nickle or cobalt.

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