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发明公开
CN101780065A 依地酸钙钠在制备抑制人或哺乳动物结缔组织生长因子、单胺氧化酶药物中的应用 无效 - 驳回

依地酸钙钠在制备抑制人或哺乳动物结缔组织生长因子、单胺氧化酶药物中的应用
摘要：
依地酸钙钠在制备抑制人或哺乳动物结缔组织生长因子、单胺氧化酶药物中的应用，依地酸钙钠在制备上述疾病药物中的应用时为注射剂，所述注射剂含有重量百分比5-30％的依地酸钙钠以及可用于注射剂的辅料；优选制成肺部靶向注射剂，含有重量百分比0.1-5％的依地酸钙钠和一种或几种适用于肺部靶向制剂的辅料，所述制成肺部靶向注射剂为微球剂，微囊剂，脂质体注射剂，所述微球、微囊、脂质体的粒径优选7-30μm，所述肺靶向制剂优选为脂质体注射液。
摘要（英）：

The invention relates to the application of calcium disodium edetate in the preparation of medicine for inhibiting connective tissue growth factor and monoamine oxidase of human beings and mammal; the calcium disodium edetate is injection when being applied to prepare the medicine of the diseases, and the injection contains 5-30wt % of calcium disodium edetate and auxiliary material used for the injection; the preferable lung target injection contains 0.1-5wt% of calcium disodium edetate and one or more auxiliary material(s) which is/are applicable to lung target preparation; the lung target injection is microsphere preparation, microcapsule preparation or liposome injection; preferably, the particle sizes of microspheres, microcapsules and liposome are 7-30 mu m; and the lung target preparation is preferably liposome injection liquid.

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