The invention discloses a driving structure of a toner cartridge and in particular relates to a driving joint structural design of the toner cartridge and a printer. A plurality of ribs are arranged along the shaft diameter direction of a driving clamping tenon; the penetrating end of each rib is provided with an oblique angled external guide angular body; a plurality of rib slots, the number of which is twice of that of the ribs, are formed along the inner diameter direction of a driving sleeve; and each rib slot is provide with an internally-oblique internal guide angular body at the opening position of the driving sleeve. The rib slots, the number of which is twice of that of the ribs, are formed on the driving sleeve, and twice of the number of the penetrating joint position is provided during rotating joint of the ribs of the driving clamping tenon, so that the ribs can be quickly and accurately inserted into the rib slots of the driving sleeve to be guided. Due to the design of the external guide angular body and the internal guide angular body of the ribs and the rib slots, the influence of interference during jointing is reduced to ensure smoother action and faults are reduced.