The invention relates to a virtual roaming design method of a nuclear power plant control room, which comprises the following steps of: setting apparatus layout modeling data of the nuclear power plant control room; setting environment setting modeling data of the nuclear power plant control room; setting evaluation reference data according to the special design analysis and verification procedure requirements for control rooms in codes and standards; and carrying out multiple-scheme interactive simulation on the apparatus layout modeling data and the environment setting modeling data according to the evaluation reference data and analyzing. The invention also relates to a virtual roaming design system of the nuclear power plant control room, which comprises an apparatus layout modeling unit, an environment setting modeling unit, an evaluation system unit and a control judging unit. The invention conducts multiple-scheme interactive simulation verification to the apparatus layout modeling data and the environment setting modeling data of the nuclear power plant control room by using a virtual roaming design, verification investment is low, the combined verification of multiple schemes can be realized, and the implementation time of a control room environment design verification project is shortened.