The invention relates to microwave irradiation pressurized sintering equipment and a use method thereof, which have the technical scheme that an upper pressing head (21) is fixedly arranged in the center of the inner wall of an upper oven cover (22) of a microwave oven, the upper part and the lower part of the inner wall of a side plate (3) of the microwave oven are respectively and fixedly provided with an upper microwave reflecting plate (20) and a lower microwave reflecting plate (7), a first waveguide tube (5) is embedded in the right side of the side plate (3) of the microwave oven, a second waveguide tube (18) is embedded in the left side of the side plate (3) of the microwave oven, the first waveguide tube (5) and the second waveguide tube (18) are respectively and fixedly connected with a first permatron (6) and a second permatron (19), a hydraulic cylinder (12) is vertically fixed in the center of a base (13), a slide block (11) passes through a chute hole of a lower oven cover (10), and a lower pressing head (8) is arranged on the upper part of the slide block (11). The invention has the characteristics that the sintering temperature can be effectively reduced, the sintering time can be shortened, microstructures of materials are convenient to control, crystal grains are thinned, the investment is saved, and the cost is low.