The invention discloses a high-voltage resistant waterproof bus duct for wind power/nuclear power/water power and a manufacturing method thereof, the bus duct comprises bare buses and composite resin bodies which are poured and wrapped on the peripheries of the bare buses, wherein the bare buses are mutually separated by the composite resin bodies, the bus duct is a whole formed by curing the bare buses and the composite resin bodies, and the bus duct does not need a metal housing. As the bare buses of the bus duct are separated by the composite resin bodies with very high insulating property, the bus duct can avoid the interphase short circuit, thereby improving the safety performance of the bus duct, leading the withstand voltage strength of the bus duct to be very high, withstanding the voltage of 35kV and protecting the safety of the bus duct during the high-voltage work. Simultaneously, as the composite resin bodies have very strong water resistance and corrosion resistance, when the bus duct works underwater for a long time, the bus duct can not be corroded, thereby better protecting a current-carrying conductor in the housing and further ensuring the normal production for power supply.