The invention discloses a method for treating waste sludge in oil and natural gas exploration drilling operations, which relates to the technical field of pollution treatment of oil and natural gas exploration drilling. The method comprises the following steps: a. microbian treatment; b. soil treatment; c. and plant treatment. The method treats the waste sludge in a biological, soil and plant combined recondition mode, effectively reduces COD, Oil and other indices in the drilling operation waste by utilizing the actions of microbian strains and degrades most organic substances into simple inorganic substances, thereby removing pollutants from the sludge and achieving the goal of harmlessness.