An insole especially advantageous for arthritic or diabetic patients comprises three layers and is shaped in a form which provides an arch support area and an integral heel receiving area. It is made from a generally foot-shaped bottom layer having a length extending from a heel area to a toe area, a top surface and a bottom surface. The bottom surface of the bottom layer preferably further comprises one to three indentations formed integrally therein. Insert layers are secured to each of said indentations. Preferably, the bottom layer is made from an EVA foam. A middle layer having a first and second side is secured to the top surface of the bottom layer adjacent the middle layer's second side. The middle layer is preferably made of a synthetic rubber layer. The middle layer takes the shape of the bottom layer. A top layer is coextensive with and secured to the first side of the synthetic rubber layer. The top layer composition is selected according to the intended use. In use, the foot of the wearer, with or without a sock or stocking thereon, rests upon the top layer in the foot-receiving compartment of the shoe.