The invention provides an air regulation system, which fully utilizes natural resource instinct physical property and roundly regulates air quality. Water serves as the medium, the air regulation system produces high-quality microclimate environment which is similar to waterfall and coast during high-speed motion to directly regulate air in a controlled room; the water resource of water molecule is from an underground reservoir which is relevant to ground temperature and is warm in winter and cool in summer; thus, air temperature approaching to the ground temperature and fresh flowing high-quality air with optimal moisture and high oxygen and anion can be obtained in the room throughout the year. In addition, a solar water heater, a thermal shield and a multifunctional safety protection window which are integrally installed at the sunny side of a house to provide hot water for daily life; meanwhile, direction irradiation of the sun to the house can be isolated in summer, and the temperature of a room under shadow can be greatly lowered; in winter, solar energy can heat the impounding reservoir and improve indoor temperature. Radiators can be installed in the room so as to utilize solar energy hot water and stored water which is warm in winter and cool in summer to form a water heating system; and two air conditioning systems can be combined to obtain better effect.