The invention discloses a device for testing the durability of a water pressure resistant grouted rock, which comprises a pressure chamber, a control cabinet, heating equipment, pressurizing equipment, measuring equipment and accessory equipment, wherein the heating equipment can supply a stable heat source for the pressure chamber; the pressurizing equipment can provide confining pressure and osmotic pressure for the pressure chamber; the pressure chamber can apply an axial pressure by means of a universal test, is corrosion resistant and can realize annular and vertical penetration tests ofthree kinds of standard samples of different dimensions at different temperatures and pressures; the measuring equipment can realize accurate measurement of temperature, pressure and flow rate; and the control cabinet can realize the accurate control of pressure and temperature. The device can be used for indoor researches on the durability of tunnel water pressure resistant grouted rock or dam impervious curtain in an environment of high-water-pressure and corrosive environment, and at the same time, realizes the researches on the change rule of the permeability of a rock sample under the coupled actions of a temperature field, a seepage field, a stress field and a chemical field.