The invention discloses a load balance optimization method of cellular cells based on X2 interface information interaction, which mainly solves the problem of limitation that load balancing behaviors only take single cell pair into consideration in a long term evolution (LTE) advanced system. The method has the technical points that: firstly, the resource state information of a neighbor cell of a target cell is reported to a source cell through adding the resource state information of the neighbor cell in a resource state updating message based on the X2 interface information interaction on the basis of the traditional load balance optimization method of the cellular cells; and secondly, invisible cells of the source cell in the neighbor cell of the target cell is defined to be Hidden cells. Due to the use of the load information of the Hidden cells during load balancing, the invention improves the load balancing effect of the overall network and can be applied in a cellular network communication system.