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发明授权
CN101838269B 1,3,8-三氮杂-螺[4.5]癸烷-4-酮类化合物及其医药用途 失效 - 权利终止

1,3,8-三氮杂-螺[4.5]癸烷-4-酮类化合物及其医药用途
摘要：
本发明涉及通式I所示的1，3，8-三氮杂-螺[4.5]癸烷-4-酮类化合物，其异构体、光学异构体、消旋体或可药用盐，含有它们的药用组合物，以及所述化合物用于制备预防或治疗手术后疼痛、偏头痛、内脏痛、神经性疼痛等各种疼痛以及由阿片类等镇痛药物引起的成瘾性和耐受性等病症的用途。
摘要（英）：

The invention relates to 1,3,8-triaza-spiro[4.5]decane-4-ketone compounds shown by a general formula I. Isomers, optical isomers, racemates or medicine salts of the 1,3,8-triaza-spiro[4.5]decane-4-ketone compounds contain the medical combinations thereof. The compounds are used for preparing, or preventing or treating various pains such as postoperative pain, migraine, visceral pain, neuropathic pain and the like and such diseases as addition and tolerance caused by analgesic drugs.

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