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发明授权
CN101843622B 脂氧素在制备女性避孕药物中的应用 有权 转让

脂氧素在制备女性避孕药物中的应用
摘要：
本发明公开了脂氧素在制备女性避孕药物中的应用。研究发现将脂氧素应用在制备女性避孕的药物中，通过提高母体血液中脂氧素的浓度，抑制受精着床所需的子宫内膜炎性微环境，从而可阻断着床。即将脂氧素应用在制备女性避孕的药物中，不仅可有效避孕，而且对肝肾功能无毒副作用，并且可重新恢复怀孕并正常分娩，符合对避孕措施所要求的能同时满足有效、安全、费用低廉、使用方便、可逆性好等条件。通过采用含脂氧素的药物抑制炎症，干预胚胎着床，是一种新型的女性避孕药物。
摘要（英）：

The invention discloses application of lipoxin in preparation of a female fertility-controlling medicament. Searches discover that the lipoxin applied in preparation of the female fertility-controlling medicament improves the concentration of the lipoxin in maternal blood and inhibits an endometrial inflammatory microenvironment required for fertilization implantation so as to block implantation.The lipoxin applied in preparation of the female fertility-controlling medicament can effectively control fertility, has not toxic or side effect on liver and kidney functions, can recover pregnancy and normal childbirth, meets the requirements for fertility-controlling measures and can meet the conditions of efficiency, safety, low cost, convenient use, good reversibility and the like. The medicament containing the lipoxin inhibits inflammation, intervenes in embryo implantation, and is a novel female fertility-controlling medicament.

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