The invention discloses a cell coiler control system, which comprises a programmable logic device, a dedicated controller, a clamp switch, a knife switch, a discharge switch, a manipulator motor, a discharge motor, a needle coiling motor and a rubberizing motor, wherein the programmable logic device is connected with the dedicated controller, the clamp switch, the knife switch and the discharge switch are respectively connected with the programmable logic device, and the manipulator motor, the discharge motor, the needle coiling motor and the rubberizing motor are respectively connected with the dedicated controller. The invention also discloses a cell coiler control method. The invention has the advantages of high control precision, low cost and good control effect.