The invention provides a liquid crystal point reversing drive circuit, comprising a positive signal source, a negative signal source, a first selection unit and a second selection unit, wherein, the positive signal source provides a first positive signal and a second positive signal; the negative signal source provides a first negative signal source and a second negative signal source; the first selection unit is connected with the positive signal source and the negative signal source and used for receiving the first positive signal of the positive signal source and the first negative signal of the negative signal source, and the unit is composed of low-voltage elements; the second selection unit is connected with the positive signal source and the negative signal source and used for receiving the second positive signal of the positive signal source and the second negative signal of the negative signal source, and the unit is composed of low-voltage elements; the first signal source is connected with the first selection unit to alternately output a first positive voltage and a first negative voltage; and the second signal source is connected with the second selection unit to alternately output a second positive voltage and a second negative voltage. The drive circuit forms output of the positive voltage and the negative voltage of two source electrodes by single positive signal source and single negative signal source, thus reducing the usage quantity of a computing amplifier.