The invention relates to a low-temperature multi-effect seawater desalting inter-regenerative multi-stage spraying raw water supply system. The system is provided with an intermediate raw water heat exchanger, raw water is heated by a one-stage or multi-stage raw water regenerative heat exchanger and is then introduced into evaporator high-temperature effective units, saline water in the high-temperature effective units is refluxed progressively, is pressurized by an intermediate raw water pump, and is then introduced into an intermediate raw water heat-exchange heater to heat the raw water of the previous stage, and the raw water of this stage is cooled to be used as the raw water of the next effective unit. Compared with a one-stage parallel-flow supply system, the invention raises the concentration ratio of the equipment, improves the heat efficiency for water production, reduces the total raw water supply amount of the equipment, lowers the unit electricity consumption for water production, reduces the heat exchange of the raw water supply and heating equipment, and lowers the equipment cost to a certain extent. Compared with a multi-stage counter-flow raw water supply system, the invention enables low-salinity raw water to correspond to high temperature effect, enables high-concentration raw water to correspond to low temperature effect, lowers the fouling tendency of the equipment, and ensures that the operation of the equipment is safer.