The invention relates to application of a microwave technology in control on disease and insect damage to tobacco. By using the microwave technology to control the disease and insect damage to tobacco, the invention can effectively control the disease and insect damage to tobacco, especially tobacco mosaic virus diseases, in the aspects of tobacco seedling raising, tobacco planting, tobacco baking and seasoning, tobacco planting soil, tobacco storage and the like, and achieves better disease and insect damage control effect. Besides, the invention can not generate pesticide residue and environmental pollution.