The invention belongs to the field of traditional Chinese medicines and discloses technology for extracting Chinese angelica and lightyellow sophora root. The extraction technology comprises the step of performing (1) solid fermentation treatment and (2) water extraction treatment on the prepared Chinese angelica and lightyellow sophora root according to a ratio in turn, wherein coprinus comatus is taken as a fermentation strain in the solid fermentation treatment. Compared with the extract obtained by common water extraction treatment, the obtained extract of the Chinese angelica and lightyellow sophora root has the characteristic of stronger anti-inflammatory effect, and is safe and reliable through toxicological test.