The invention provides a dynamic coordinate control method of full-face large-scale tunneling equipment, which belongs to the technical field of tunneling automatic control and solves the problem of multi-system coordinate control over the tunneling equipment under a multi-field coupling action. The dynamic coordinate control method of the full-face large-scale tunneling equipment comprises a sealed cabin pressure distribution real-time dynamic model, an advancement speed set value model, a cutter rotation speed set value model and a slag discharge speed set value model, and is characterized in that: a system automatically corrects the set values of the advancement speed of the tunneling equipment, the rotation speed of a cutter and the slag discharge speed of a spiral conveyor in real time according to the pressure change of a sealed cabin of the tunneling equipment and therefore realizes the automatic real-time coordinate control of each sub-system. The dynamic coordinate control method of the full-face large-scale tunneling equipment has the advantages that: an advancement sub-system, a cutter sub-system and a slag discharge sub-system can be coordinately controlled; the control of the dynamic balance of the pressure of the sealed cabin is realized; and the whole tunneling process is safe and highly efficient.