The invention discloses oral liquid of honeysuckle flower and baical skullcap root and a preparation method thereof. The medicament consists of honeysuckle flower extract and baical skullcap root extract, and is characterized in that every 1ml of solution comprises no less than 18.0mg of baical skullcap root extract based on the amount of baicalin and no less than 3.0mg of honeysuckle flower extract based on the total amount of chlorogenic acid and 4-O-caffeoylquinic acid, wherein the proportion of the chlorogenic acid to the 4-O-caffeoylquinic acid is 5:4-2:1; and the PH value of the solution is 5.5 to 5.9. The medicament has the advantage of more stable quality.