The invention relates to a liquid crystal display device which comprises a first substrate, a second substrate and a liquid crystal layer configured between the first substrate and the second substrate. The first substrate comprises a glass substrate and a first transparent electrode layer, a first transparent insulating layer, a second transparent insulating layer and a second transparent electrode layer which are configured on the glass substrate layer by layer. The second transparent insulating layer comprises a plurality of first convex blocks and a plurality of second convex blocks. One first convex block and one second convex block are arranged in each pixel region. The second transparent electrode layer comprises a plurality of electrode patterns which respectively cover the first convex blocks and a plurality of second electrode patterns which respectively cover the second convex blocks. A strong electric field is generated between the first transparent electrode layer and the first electrode patterns and the second electrode patterns, and an auxiliary horizontal electric field is simultaneously generated between the first electrode patterns and the second electrode patterns, thereby reducing the operation voltage. In addition, the invention further provides a manufacturing method of an electrode substrate so as to reduce the distance between the first transparent electrode layer and the second transparent electrode layer and further reduce the operation voltage.