The invention relates to a CNC (Computerized Numerical Control) drilling machine for processing pipe fittings. The upper part of the machine bed is provided with a main shaft rotary device and a transmission guiding device, a drilling platform and a clamping tailstock are movably arranged on the transmission guiding device, a pipe wall clamping assembly and a drilling assembly are arranged on thedrilling platform, a pipe end clamping chuck is arranged on the main shaft rotary device and the clamping tailstock, the main shaft rotary device is also provided with a motor for driving a main shaft and the chuck to rotate, and a CNC console is adopted for electric and hydraulic control. The invention can be used for processing various metallic or nonmetallic pipe fittings in a plurality of specifications, has the advantages of large processing range and favorable suitability, adopts numerical programming control and can be used for automatically, conveniently and safely processing the outer wall holes of the pipe fittings with high efficiency.