The invention relates to a medicament for easing the pain of a human body and a preparation method thereof, in particular to a medicament composition with the functions of promoting blood circulation and removing blood stasis, resisting inflammation and diminishing swelling and easing pain, and a preparation method thereof. The medicament composition comprises the raw materials as follows: 20-100parts by mass of Chinese teasel root, 20-110 parts by mass of cape jasmine fruit, 10-100 parts by mass of baikal skullcap root, 20-100 parts by mass of angelica root and 3-20 parts by mass of borneol. The preparation method of the medicament composition comprises the following steps of: (1) extracting the raw materials of the medicament composition except the borneol with water or an ethanol solution, filtering, and collecting the filtrate as an extract 1; and (2) adding the borneol to obtain he medicament composition, wherein the percent of the ethanol in the ethanol solution by volume is more than 0 and less than or equal to 85%, and the mass ratio of the raw materials to the water or the ethanol solution is 1: 5-8. Clinical experiments show that the medicament composition has good curative effect for easing the neck/shoulder pain, the lumbocrural pain, the joint pain and the muscle pain caused by the rheumatism, the osteoproliferation, tumble and sprain, and the like.