The invention discloses a method for comprehensively utilizing burdock roots in tobacco, which belongs to the technical field of cigarette. The technical scheme of the invention comprises the following steps: (1) preparing dry powder of burdock roots; (2) performing water extraction to obtain the extract-type water extract of burdock roots serving as tobacco spice with a wetting function; and (3)manufacturing a substrate of tobacco sheets by using filter residue. In the invention, a great amount of resources are available and the cost is low; the extract has functions of improving flavor andwetting at the same time; and the waste residue is used for manufacturing the substrate of the tobacco sheets, therefore, the lack of raw materials of the tobacco sheets by a papermaking method is relieved, and the sensory quality of the tobacco sheets by the papermaking method can be improved. The method of the invention ensures no waste during the processing and the comprehensive utilization ofthe burdock roots is realized.