The invention relates to a method for coordinating and refining high-strength and high conductivity copper alloy crystal particles by using room temperature multidirection deformation and annealing process, which comprises the following steps of cutting high-strength and high conductivity copper alloy ingot or thermal deformation section into rectangular blocks, putting the blocks in a furnace, heating to 800 to 860 DEG C, preserving the heat for 40 to 120 hours, quenching with water, cooling and carrying out multi-round and multi-axis compression deformation in sequence along an X axis, a Y axis and a Z axis of the rectangular blocks, and controlling the true dependent variable of each round to be 0.2 to 0.6, annealing and recrystallizing at 600 to 800 DEG C when the accumulated true dependent variable is more than 1.2 so that superfine crystal particle copper alloy blocks of which the mean size is 0.5 to 3 mum are obtained. The method has simple requirements on processing technique and equipment, is convenient for operation, and is capable of effectively overcoming the defects of serious damage of moulds, too high requirements on power and difficult preparation of block materials in the process of refining the high-strength and high conductivity copper alloy crystal particles in the prior art; in addition, the method can be used for preparing a large dense superfine crystal particle copper alloy material and has good industrial application prospect.