The invention provides a high-fluorine mixcrystal coating solar photovoltaic cell back panel and a manufacture method thereof, belonging to the technical field of solar cell back panels. The back panel comprises a structure in which seven layers are arranged from the top to the bottom, wherein a first high-fluorine mixcrystal coating is coated between the lower surface of a first substrate and the upper surface of a second substrate; a second high-fluorine mixcrystal coating is coated between the lower surface of a third substrate and the upper surface of a fourth substrate; and a PET layer is coated between the lower surface of the second substrate and the upper surface of the third substrate. By adding mixture consisting of high-hardness inorganic micro-nano powder and silicon dioxide nano-powder for coating a coupling agent into the high-fluorine mixcrystal coating, the hardness of the coating is greatly improved, the scratching resistance is excellent; and the coating surface of the back panel cannot be damaged when the silicon sealant on the surface is removed, the quality is ensured, the service life of the components is increased to ensure the service life of the componentsto be more than 25 years.