The invention discloses a Chinese medicine preparation for treating purulent ulceration, which comprises weeping forsythiae capsule, rhubarb, raw kusnezoff monkshood root, Chinese angelica, pangolin scales, centipede, frankincense, hydrargyri oxydum rubrum, lead powder, typhonium giganteum, croton frost, fresh rehmannia, ephedra, snake slough, radix scrophulariae, myrrh and snake gall. The adopted medicines are pure Chinese herbal medicines which are in reasonable synergic compatibility; and the Chinese medicine preparation has obvious curative effect on the ulceration diseases such as purulent ulceration, breast abscess, postoperation bedsore and the like caused by operation infection or bacterial infection, ensures rapid elimination of clinical symptoms, has the characteristics of shorttreatment course, low cost, low toxic and side effects and the like, and is convenient to use.