The invention provides a preparation method for a traditional Chinese medicine composition with antibacterium and antiphlogosis efficacies. The composition is prepared from the following raw materials in parts by weight: 76.5-261.45 parts of rheum officinale, 45-107.1 parts of cogongrass rhizome, 22.5-50.4 parts of liquorice, 5-10 parts of chloridion neutralizer, 10-15 parts of heavy metal chelant, 15-30 parts of acid agent, 20-40 parts of alkali agent and 2-5 parts of lubricant, wherein a disintegrating agent comprises the acid agent and the alkali agent. The preparation method comprises thefollowing steps: evenly mixing the traditional Chinese medicine fine powder, the chloridion neutralizer, the heavy metal chelant and the acid agent of the disintegrating agent to obtain powder A; evenly mixing the alkali agent of the disintegrating agent to obtain powder B; mixing the powder A and the powder B, adding the lubricant, and evenly mixing; and directly tabletting the mixed powder, thus obtaining traditional Chinese medicine effervescent tablets. The preparation method is simple in process and is suitable for requirements of scale industrial production.