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发明授权
CN102018660B 萘哌地尔栓剂及其制备方法 有权

萘哌地尔栓剂及其制备方法
摘要：
本发明涉及一种萘哌地尔栓剂，其按重量份计包括如下组分：萘哌地尔10～25份，油脂性基质10～60份，水溶性基质10～60份，表面活性剂1～10份，硬化剂10～30份，吸收促进剂5～15份。本发明的栓剂分散均匀，溶出率稳定，提高了生物利用度和药物的有效性。
摘要（英）：

The invention relates to naftopidil suppository and a preparation method thereof. The naftopidil suppository comprises the following components in part by weight: 10 to 25 parts of naftopidil, 10 to 60 parts of oleaginous substrate, 10 to 60 parts of water-soluble substrate, 1 to 10 parts of surfactant, 10 to 30 parts of hardening agent and 5 to 15 parts of absorbefacient. The suppository is uniformly dispersed, has high dissolution rate and improves the bioavailability and the effectiveness of medicaments.

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