The invention discloses a process for producing a ceramic tile with uneven surface. The process comprises the following steps: (1) blank, over glaze and fancy glaze are prepared; (2) the blank is molded into a blank tile in a mould tile, wherein uneven grains with depth of between 1.0 and 2.5mm are formed in the mold tile, and the pressure for molding the blank is between 3,300 and 3,700MPa/cm<2>; (3) the molded blank tile is sintered and dried, wherein the sintering temperature is between 1,170 and 1,200 DEG C; (4) the glaze is poured on the dry tile, wherein the flowability of glaze slurry is between 30 and 40S/100M<1>, the fluctuation is between 0 and 5S, the specific gravity of the glaze slurry is between 170 and 190g/cm<2>, and the quantity of the glaze is between 0.01 and 0.08g/cm<2>; (5) the fancy glaze is printed by a soft roll, wherein the proportion between pigment and water in the fancy glaze is between 1.37 and 1.45, the rotating speed of the soft roll is matched with thatof a tile conveying belt, and is set to be 30 to 40m/min; (6) sintering the tile in a kiln, wherein the sintering temperature is between 1,090 and 1,110 DEG C; and (7) trimming. By the process for producing the ceramic tile with uneven surface, the produced ceramic tile with uneven surface has good printing visual effect on the uneven surface, and has strong three-dimensional sensation.