The invention discloses a novel low pressure tank drawer dropping-resistant device comprising an anti-falling block and a guide rail, wherein the anti-falling block is fixed on the middle of the outer plate surface of the left side plate of a drawer by a bolt and can rotate around the bolt; the front end of the anti-falling block is provided with an inward spacing column, and the rear end of the anti-falling block is provided with a downward hanger; the front end of the guide rail is provided with an upward spacing lug; and the position in front of the bolt on the left side plate of the drawer is provided with a spacing round hole. When the drawer is positioned in a drawer compartment, the spacing column warps upwards to be supported and connected to the top in the spacing round hole; meanwhile, and the hanger sags to be in lap joint on the top of the guide rail; when the drawer slides outwards to the middle and exposes out of the drawer compartment, the hanger can hook the spacing lug; and when the spacing column is pressed downwards to the bottom in the spacing circular hole, the hanger can separate from the spacing lug. The invention has the characteristics of simple structure and the like, and is flexible in operation and reliable in interlocking.