The invention discloses a medicament for treating cyclomastopathy and breast fibroadenoma. The medicament comprises the following components in parts by weight: 27-31 parts of Chinese thorowax root, 28-33 parts of parched tangerine seed, 34-37 parts of radix curcumae, 27-31 parts of calcinated oyster, 37-42 parts of chekiang fritillary bulb, 38-44 parts of seaweed, 36-42 parts of curcuma zedoary,38-42 parts of tulip bulb, 32-38 parts of selfheal, 26-32 parts of Chinese angelica, 33-38 parts of szechwan lovage rhizome, and 32-36 parts of tangerine pith. The preparation method of the medicament comprises: mixing the components, grinding into powder, adding honey into the powder (130-140 g honey per 100 g powder), and preparing the mixture into pills (8.5-9.5 g per pill). The pill is administered each in the morning, at noon and at night, and one month is a course of treatment. The medicament can be used for simultaneously treating cyclomastopathy and breast fibroadenoma, and has the advantages of simplicity in administration, good curative effect, quick action, no recurrence, and no adverse effect.