The invention discloses an electromagnetic shielding vapor sealing zipper and a preparation method thereof. The electromagnetic shielding vapor sealing zipper comprises a composite conductive base cloth, a chain, a copper alloy pulling head, an upper stop, a lower stop, an upper sealing head and a lower sealing head, wherein the chain consists of sprockets which are fixed on the composite base cloth and coupled with one another; the upper end of the chain and the upper stop are fixed on the upper sealing head in a vulcanization moulding, injection moulding or casting moulding mode; the lower end of the chain and the lower stop are fixed on the lower sealing head in a vulcanization moulding, injection moulding or casting moulding mode; and the copper alloy pulling head is arranged on the chain. The electromagnetic shielding vapor sealing zipper has the advantages that: electromagnetic radiation can be effectively shielded; anti-static performance, blocking performance and fire resistance are high; no residue glue is on the surface of the zipper prepared by the method, so that the product is not polluted and clean and attractive appearances of the zipper and the product are not influenced; the blocking sealing effect is good; and the wide application range includes large-scale and minitype electronic equipment electromagnetic radiation-resistant sealing protection, individual protection equipment and ammunition package.