The invention discloses a high-rigidity and high-precision nut seat driving connection device for high-precision connection of a static pressure guide rail and a ball screw in a precision grinder. The device comprises a lead screw (6), a lead screw nut (4) matched with the lead screw (6), a nut connecting sleeve (5) connected with the nut (4), and a guide rail connecting plate (1) sleeved outsidethe nut connecting sleeve (5); and the periphery of the guide rail connecting plate (1) is provided with four same stop blocks (2), two same stop block covers (7), three rollers (3), (8) and (10) with same shapes and sizes and different functions fixed on the vertical surface of the lead screw (6), anti-rotating stop blocks (9) and (11) and a stop block connecting plate (12), wherein a line contact structure is adopted among the stop blocks, the rollers and the guide rail connecting plate. An anti-rotating roller (10) is linearly contacted with the anti-rotating stop blocks (9) and (11), gapsare formed between the anti-rotating roller (10) and the guide rail connecting plate (1) and the stop block connecting plate (12), and the axial direction of the lead screw (6) is provided with a gap; thrust stop rollers (3) and (8) are linearly contacted with the guide rail connecting plate (1) and the stop block covers (7), gaps are formed between the thrust stop rollers (3) and (8) and the twothrust stop blocks (2), and the radial direction of the lead screw (6) is provided with a gap. By adopting the structure, the device ensures axial rigidity, eliminates reverse clearance, can eliminate the influence of bending of the lead screw on the moving precision of a workbench, solves the problems that the nut and the lead screw have high abrasion, are not easy to adjust and are difficult toinstall, and is adaptive to the high-precision and high-rigidity processing requirements of the precision grinder.