The invention discloses salt-tolerant latex cement slurry for well cementation, which comprises the following components: cement, salt tolerant latex which is 4-40% of weight of cement, water-loss control agent which is 3-4% of weight of cement, slow-release agent which is 0-2% of weight of cement, dispersant which is 0.5-3% of weight of cement, saline or seawater with concentration not higher than 15% which is 18-51% of weight of cement, and antifoaming agent which is 0.5-1.3% of weight of cement. The salt-tolerant latex cement slurry provided by the invention overcomes the shortcoming that ordinary latex is not salt tolerant, so that the salt-tolerant latex cement slurry system can be used for cementing a complex well with a salt bearing rock formation (salt formation, salt and gypsum formations, saltwater formation). In addition, the salt-tolerant latex cement slurry provided by the invention can be also directly prepared from seawater, so as to reduce the fresh water transportation load of well cementing operation in an offshore drilling platform, and reduce operation cost.